Abstract

In acute coronary syndromes (ACSs), longer decision delay – the time patients wait before seeking medical attention after symptoms have started – increases the risk of complications and death. However, many patients wait much longer than recommended and research is needed investigating how patient decision delay can be reduced. In a cross-sectional study of 120 ACS survivors, we investigated the relationship between knowledge of cardiovascular risk factors and decision delay. Several days after the onset of a cardiac event, patients completed a questionnaire measuring demographics, decision delay, objective knowledge of cardiovascular risks factors and of ACS symptoms, and subjective perceptions of symptoms during the cardiac episode. Relevant clinical data were extracted from patients’ medical records. In a multiple linear regression analysis, controlling for demographic and clinical factors, objective knowledge of cardiovascular risk factors and ACS symptoms, and subjective attributions of symptoms to a cardiac cause were related to shorter decision delays. Among patients with relatively high knowledge of risk factors, only 5% waited more than 1 h to seek help, compared to 22% among patients with relatively low knowledge. These results suggest that knowledge of the factors that increase the risk of developing cardiovascular disease could play a role in patient decision making during an acute cardiac event. We discuss methodological issues and potential underlying mechanisms related to decision heuristics and biases, which can inform future research.

Highlights

  • Cardiovascular disease is the most common cause of death worldwide, responsible for 25% of deaths in Europe and causing more premature deaths than cancer (Heron, 2016; World Health Organization, 2016; World Health Statistics, 2018)

  • We investigated for the first time whether knowledge about cardiovascular risk factors is related to decision delay in patients experiencing an acute coronary syndromes (ACSs)

  • To the best of our knowledge, this is the first study showing that patients’ correct identification of cardiovascular risk and protective factors is related to shorter decision delays in seeking for help

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Summary

INTRODUCTION

Cardiovascular disease is the most common cause of death worldwide, responsible for 25% of deaths in Europe and causing more premature deaths than cancer (Heron, 2016; World Health Organization, 2016; World Health Statistics, 2018). Such symptom knowledge is usually assessed with objective measures (i.e., patients’ correct recognition of the symptoms in a test-like questionnaire) or subjective measures (patients’ self-reported knowledge of the symptoms before the cardiac event) Both types of measures have shown mixed results in relation to prehospital delays (Arrebola-Moreno et al, 2020a). We investigated for the first time whether knowledge about cardiovascular risk factors is related to decision delay in patients experiencing an ACS. To account for other factors that could influence patient decision making (Nguyen et al, 2010; Arrebola-Moreno et al, 2020a), we investigated the effect of patients’ objective knowledge of ACS symptoms, subjective attributions of symptoms to cardiac causes, perceived severity of symptoms, and demographic factors. Our hypothesis was that patients’ knowledge about cardiovascular risk factors would be uniquely related to decision delay after accounting the effect of the other factors

MATERIALS AND METHODS
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DATA AVAILABILITY STATEMENT
ETHICS STATEMENT
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