Abstract

Zika virus is currently a highlight topic in the field of global health. Zika virus outbreaks in some countries including in Singapore have been making people worried and causing health official in any country to prevent Zika from becoming entrenched and spreading in population in the world. In 2016, it was reported a few countries in the Americas declared endemic Zika virus such as El Salvador, Venezuela, Colombia, Brazil, Honduras, Mexico and Panama. While countries in Asia, including Indonesia expressed as sporadic areas Zika virus. Zika virus is a virus that is transmitted through the bite of Aedes mosquito genus, the same as the genus of mosquitoes causing dengue fever and chikungunya. The virus can also be transmitted through sexual intercourse with an infected person Zika virus. About 20% of people infected with Zika virus has clinical symptoms such as fever, skin rashes, muscle and joint pains, eadache and conjunctivitis. Zika virus incubation period of about 2-7 days. Zika virus is a virus Flaviridae family that was first discovered the mosquito Aedes africanus in 1947 and allegedly did not attack humans. But later, it was found clinical symptoms in humans in 1953 which were caused by Zika virus in Nigeria. Antibodies in Uganda at that time showed approximately 6% of the population have antibodies to Zika virus. Examination of antibodies against the virus in humans were found positive in many countries today, such as in Egypt, South Africa, India, Malaysia and Indonesia. In Indonesia and another countries in Southeast Asia, the sporadic of Zika virus has been occurring for the last 6 years.

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