Recognitive characteristics in patients with cerebrovascular disease in different cerebral areas

Abstract

Objective To study the recognition in patients with cerebrovascular disease in different areas. Methods The recognitive tests including Chinese words recognizing test and nonsense pictures recognizing test were accomplished in computer, and the differences of recognitive functions between patients with cerebrovascular disease (70 cases, they divided into basal ganglia damaged group, frontal lobe damaged group and temporal lobe damaged group according to damaged brain areas;divided into cortex group and under cortex group according to damaged gray matter or white matter;divided into left and right hemisphere groups according to different damaged hemispheres) and normal controls(75 cases) were compared. The scores of patients with cerebrovascular disease in different cerebral areas were compared too. Results The two scores of the Chinese words recognizing test and nonsense pictures recognizing test in patients with cerebrovascular disease (10.13±2.72,9.50 ±3.02) were significantly lower than that in normal controls( 12.96 ±2.97,13.35 ±2.56) ( t_1 = 5.98, t_2=8.30, both P<0.01) , and in patients with cerebrovascular disease focuses in cortex (9.08 ±2. 11, 8.26 ±2.72)were lower than that in patients with cerebrovascular disease focuses in under cortex(11.38 ±2.86, 10.97 ±2.72) (t_1 = 3.86, t_2=4. 15, both P<0.01) ;the scores of Chinese characters recognizing test in patients with left hemisphere lesion(9. 33 ± 2.61) was lower than that in patients with right hemisphere lesion( 10. 84 ± 2.65 ) ( t ,= 2. 39, P < 0. 05 ). The scores of all tests in patients with cerebrovascular disease focuses in basal ganglia,frontal lobe and temporal lobe were significantly different(F_1 =10.00, F_2 = 11.64, both P<0.01). The scores of the two tests in patients with cerebrovascular disease focuses in temporal lobe(8. 30 ± 2.08, 7. 35 ± 2. 83 ) were lower than that in patients with cerebrovascular disease focuses in basal ganglia(11. 38 ± 2. 86, 10.97 ±2.72) and frontal lobe(9. 94 ± 1. 83, 9.28 ±2.24) (P<0.01, P<0.05) ;the scores of the two tests in patients with cerebrovascular disease focuses in frontal lobe(9.94 ± 1. 83, 9.28 ± 2. 24) were lower than that in patients with cerebrovascular disease focuses in basal ganglia(11. 38 ±2.86, 10.97 ±2.72) (P<0.05). Conclution The disturbances of recognition were observed in patients with cerebrovascular disease. The disturbances of recognition in patients with cerebrovascular dis-ease focuses in cortex were more serious than that in patients with cerebrovascular focuses in under cortex;the disturbances in patients with temporal lobe lesion were most serious. Key words: Cerebrovascular disease; Recognition memory; Different areas