Abstract

Simulated and experimental multivariate dependences observed on spectrometric acid-base titration of polyribonucleic acid were examined. Examination of the simulated data revealed the possibility for differentiating distribution diagrams of polymer species produced by complex formation with single- and double-stranded infinite polymers under conditions of incomplete concentration and spectral selectivity. The protonation constants of polycytidylic polyribonucleic acid were calculated from experimental data by using the developed chemometric procedure.

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