Abstract
To assess the sensitivity of Warrington's Recognition Memory Test (RMT) “Words” and “Faces” subtests to lateralized temporal lobe seizure foci and effects of epilepsy surgery, 27 left- and 39 right-temporal lobectomy patients were tested before and after surgery. Only surgical patients who were seizure-free after surgery were studied. The temporal lobectomy patients were compared to 50 seizure patients who were tested twice without having undergone surgery. RMT scaled scores were analyzed using a 3 × 2 × 2, Group by Pre-post by Content repeated measures ANOVA, which revealed significant Group by Pre-post, Group by Content, and Pre-post by Content interactions. A 3 × 2, Group by Pre-post repeated measures ANOVA of the discrepancy between Words and Faces raw scores revealed a significant Group effect only. Left-temporal lobectomy patients tended to show smaller raw score discrepancies than right-temporal lobectomy patients and seizure controls. Attempts to classify patients as having left- or right-temporal epileptogenic pathology on the basis of difference scores (as described in the RMT manual) revealed that left-temporal patients were frequently misclassified as right temporal; however, those who met classification criteria for left-temporal dysfunction included few patients with right-temporal seizures.
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