RECESSIVE DYSTROPHIC EPIDERMOLYSIS BULLOSA ORAL LESIONS: A CASE REPORT

Abstract

Epidermolysis bullosa (EB) is a heterogeneous group of rare genetic disorders characterized by fragility of skin and mucous membranes, in which blistering lesions may arise spontaneously or by minor friction. There may be marked oral involvement, creating devastating alterations in the soft and hard tissues. The following case report describes the oral lesions observed in a 41-year-old female patient diagnosed as having recessive dystrophic epidermolysis bullosa (RDEB). She has been under medical assistance for the skin lesions and was under amoxicillin-clavulanate and silver sulfadiazine therapy. Oral examination revealed a 1-cm bullous lesion and 2 ulcerations on the dorsum of the tongue. Moreover, atrophy of filiform papillae in the anterior third of the tongue and ankyloglossia were also observed. Oral lesions have been controlled under topical treatment with a solution of clobetasol propionate 0.05% administered with nystatin 100,000 IU/mL every 8 hours. Epidermolysis bullosa (EB) is a heterogeneous group of rare genetic disorders characterized by fragility of skin and mucous membranes, in which blistering lesions may arise spontaneously or by minor friction. There may be marked oral involvement, creating devastating alterations in the soft and hard tissues. The following case report describes the oral lesions observed in a 41-year-old female patient diagnosed as having recessive dystrophic epidermolysis bullosa (RDEB). She has been under medical assistance for the skin lesions and was under amoxicillin-clavulanate and silver sulfadiazine therapy. Oral examination revealed a 1-cm bullous lesion and 2 ulcerations on the dorsum of the tongue. Moreover, atrophy of filiform papillae in the anterior third of the tongue and ankyloglossia were also observed. Oral lesions have been controlled under topical treatment with a solution of clobetasol propionate 0.05% administered with nystatin 100,000 IU/mL every 8 hours.