Abstract

The use of confocal microscopy and fluorescent dyes permitted us to show that the nucleus plays an important role in excitation-contraction and secretion coupling of several excitable and non excitable cells. In addition, our group suggested that, like the sarcolemmal membrane, the nuclear envelope membrane possesses receptor s and channels which may play an important role in modulating Ca2+ influx and cytosolic Ca2+ buffering capacity of the nucleus.

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