Receptive field sizes and responsiveness to light in area 18 of the adult cat after chiasmotomy. Postoperative evolution; role of visual experience.

Abstract

Receptive field sizes to stimulation of the ipsilateral temporal retina were studied in area 18 of adult cats at different times after complete midsagittal section of the optic chiasm. A specific postoperative evolution could thus be noticed: immediately after section, the average area of the receptive fields was reduced, as compared to control preparations, owing to the disappearance of large fields located at more than 20 degrees of eccentricity. A progressive reappearance of these large fields occurred between 8 and 45 days after chiasmotomy, provided that the animal was placed in normal visual conditions during its postoperative period. No such recovery could be assessed after as long as 55 days, in animals kept in complete darkness after operation. Chiasmotomized cats also displayed a reduction of their percentage of light reactive cells with respect to controls, as expected from the suppression of the contralateral input. This percentage was at first very low and progressively increased, during postoperative recovery but again not when the animal had been kept in the dark. Finally, an increase of cells with "diffuse responses" was observed in the late postoperative recovery stage. This latter evolution also appeared to depend upon postoperative visual experience. On the other hand, no clear indication of an interhemispheric transfer could be obtained in these experiments, even at the 17-18 boundary.