Receptive Anal Intercourse: Impact on Colorectal and Urologic Diagnoses.

Between January 1, and October 31, 1987, 420 homosexual men who participated in a cohort study of infection with the human immunodeficiency virus (HIV) completed a questionnaire that examined their sexual practices during the previous six months. Of the subjects, 205 (48.8%) men were HIV-seropositive and 215 (51.2%) men were HIV-seronegative. Although there was an appreciable level of condom usage in both groups, 13.5% of the HIV-seronegative men had engaged in unprotected receptive anal intercourse and 6.3% of the HIV-seropositive men had engaged in unprotected insertive anal intercourse. Condom breakage was reported on approximately 6% of occasions by a minority of subjects. Among subjects who were in a relationship with a regular male sexual partner, the most commonly reported sexual practices were deep kissing, mutual masturbation and receptive oral intercourse without ejaculation. No HIV-seronegative man engaged in unprotected receptive and/or insertive anal intercourse, receptive oral intercourse with ejaculation or receptive and/or insertive "fisting" with a regular partner who was HIV-seropositive. No HIV-seropositive man engaged in unprotected insertive anal intercourse to ejaculation with an HIV-seronegative partner, although they did so with partners who were HIV-seropositive or of unknown status. On multivariate analyses the subject's antibody status was found to be associated with receptive anal intercourse with a condom (P = 0.007) and mutual masturbation (P = 0.001), with HIV-seronegative men being more likely to practise either; no significant independent effect was associated with the partner's antibody status. These findings provide important information on the types and levels of sexual practices in a group of homosexual men after the recognition of the acquired immunodeficiency syndrome in this country.

A Systematic Review of Inflammatory Bowel Disease Epidemiology and Health Outcomes in Sexual and Gender Minority Individuals

Sexual Health Outcomes in Sexual Minority and Heterosexual Men After Prostate Radiation Therapy.

Anorectal Sexual Function Index: Development and Validation of a Health-related Quality of Life Measure

A total of 246 healthy male sexual contacts of men with either acquired immunodeficiency syndrome (AIDS) or an AIDS-related condition were recruited into a prospective study in Toronto, Canada between July 1984 and July 1985. At induction, data were collected on the sexual relationship between the contact and his primary case, sexual activities with other men, history of sexually transmitted diseases and other diseases, and use of recreational drugs. At recruitment, 144 sexual contacts had antibodies to human immunodeficiency virus (HIV); 102 of the contacts were seronegative at induction and at three months following recruitment. No association between HIV seropositivity and total number of sexual partners could be demonstrated. In univariate and multivariate analyses, receptive and insertive anal intercourse with the primary cases, and activities which either indicated or potentially caused anorectal mucosal injury (rectal douching, perianal bleeding, receipt of objects in ano, and receptive fisting) were strongly associated with HIV seropositivity. In the final multiple logistic regression model, two significant interaction effects were observed: the interaction between receptive anal intercourse and insertive anal intercourse and that between receptive anal intercourse and the anorectal mucosal injury index. These two interaction terms had negative regression coefficients which suggested that change in one sexual activity would not decrementally reduce risk of HIV infection without a comparable modification in the other activity. No association could be demonstrated between oral-genital and oral-anal sexual contact and odds ratios for these sexual activities declined to levels below 1.0 when adjusted for frequency of receptive anal intercourse.

BackgroundNoise exposure is considered a stressor that may potentially exert negative health effects among the exposed individuals. On a population basis, the most prevalent and immediate response to noise is annoyance, which is an individually experienced phenomenon that may activate physiological stress-responses and result in both physical and mental symptoms. Health implications of traffic noise have been investigated thoroughly, but not of neighbour noise. The aim of the present study was to examine the associations between neighbour noise annoyance and eight different physical and mental health symptoms.MethodsCross-sectional data from the Danish Health and Morbidity Survey 2017 were used. The present study included a random sample of 3893 adults living in multi-storey housing. Information on neighbour noise annoyance and various health symptoms (e.g. pain in various body parts, headache, sleeping problems, depression, and anxiety) during the past two weeks was obtained by self-administered questionnaires. The question on neighbour noise annoyance and health symptoms, respectively, had three possible response options: ‘Yes, very annoyed/bothered’, ‘Yes, slightly annoyed/bothered’, ‘No’. The associations between neighbour noise annoyance and very bothering physical and mental health symptoms were investigated using multiple logistic regression models.ResultsBeing very annoyed by neighbour noise was significantly associated with higher odds of being very bothered by all eight health symptoms (adjusted OR = 1.73–3.32, all p-values < 0.05) compared to individuals not annoyed by noise from neighbours. Statistically significant interactions were observed between sex and two of the eight health symptoms. Among women, a strong association was observed between neighbour noise annoyance and being very bothered by pain or discomfort in the shoulder or neck, and in the arms, hands, legs, knees, hips or joints. Among men, no associations were observed.ConclusionsBased on the findings from this study, neighbour noise annoyance is strongly associated with eight different physical and mental health symptoms. Future studies are encouraged to 1) determine the direction of causality using a longitudinal design, 2) explore the biological mechanisms explaining the sex-specific impact of neighbour noise annoyance on symptoms of musculoskeletal pain or discomfort and the other outcomes as well.

IntroductionLocal guidelines changed in 2019 recommending triple site chlamydia and gonorrhoea testing for all men who have sex with men (MSM) regardless of sexual history. The evidence base for this...

Introduction Most health-related quality of life (HRQOL) measures after prostate cancer treatment do not account for receptive anal intercourse (RAI). Our group developed the anorectal sexual function index (ASFI), which assesses sensation during RAI and associated satisfaction and bother. Objective We aimed to describe anorectal sexual function in a group of men with prostate cancer. Methods In July 2024, we initiated a mixed-method study of RAI habits among cisgender men. To be eligible, they must have engaged in or attempted RAI within the past 6 months and have either 1) an issue with RAI (pain, lack of pleasure, bleeding, etc.) or 2) an active urologic/colorectal diagnosis. All participants underwent a medical interview via Zoom (~30 minutes) during which all medical diagnoses were verified. The participants then completed HRQOL life questionnaires, including the ASFI, EPIC, AUA symptom score, and a measure for sexual satisfaction (NSSS). We provide descriptive statistics of our sample with a diagnosis of prostate cancer and calculated a correlation matrix of scales. Results Twelve patients had a diagnosis of prostate cancer. Table 1 shows the details of each case and HRQOL scores. Treatments included prostatectomy (n=2), radiation +/- ADT (n=3), focal therapy (n=3), and active surveillance (n=3). The average age was 64 years (standard deviation 8). Most participants identified as gay/bisexual; however, two participants identified as straight who enjoy prostate play with their wives. Excluding those on active surveillance, after prostate cancer treatments, 4 (44%) complained of RAI anhedonia, 1 (11%) complained of pain, and 4 (44%) reported no change in RAI sensation. ASFI pleasure scores correlate moderately with sexual satisfaction (r=0.55) but only weakly with EPIC sexual function scores (r=0.25). ASFI pain scores negatively correlate with ASFI pleasure (r=-0.55) and orgasm frequency (r=-0.52). ASFI urinary scores poorly correlate with AUA symptom score (r=-0.03) and EPIC urinary function scores (0.15). Two men were recently diagnosed with prostate cancer and were currently making treatment decisions with the hope to preserve anorectal sexual function. Conclusions RAI anhedonia and pain can occur after prostate cancer treatments although some participants report no change in sensation. Traditional HRQOL measures do not fully capture the RAI experience as measured by the ASFI. Measuring RAI sensation prior to treatment is necessary as at least one participant had RAI pain without cancer treatments. More research is necessary to determine which treatment modality best preserves RAI function. Anorectal sexual function appears to be a factor in the treatment decision making process. Disclosure No

MP74-16 MEASURING SEXUAL FUNCTION AFTER TREATMENT FOR PROSTATE CANCER IN MEN WHO HAVE SEX WITH MEN: A HIDDEN DOMAIN EMERGES

Understanding the Experience of Receptive Anal Intercourse in Patients With Chronic Pelvic Pain Syndrome.

BackgoundCurrent epidemiological evidence suggests that receptive anal intercourse (RAI) considerably increases the risk of HIV infection per sex act (RRRAI) compared to vaginal intercourse (VI). RAI may increase HIV risk...

BACKGROUND:Mental health has been impacted by COVID-19 throughout the United States and beyond. The mental health and well-being were further affected with excessive substance use during the pandemic. The aim of this research was to explore how the COVID-19 affects the mental health of the young adults (18–24 years) in the South Jersey area. We also examined the association between mental health symptoms in young adults and substance use during the first and second year of the pandemic.METHODS AND MATERIAL:A cross-sectional survey was conducted with (n = 711) 527 participants that included young adults (18–24 years old) across university campus in south jersey and in the community cohorts. Multinomial regression analysis and Chi-squared test were used to explore the association between mental symptoms and substance use. Data were analyzed using Microsoft Excel Spreadsheet for descriptive statistics and Python 3.0 scikit-learn package.RESULTS:The study showed that “Lonely” and “Hopeless” were the top two mental health symptoms. It was observed that the symptoms of “Lonely” and “Hopeless” increased for both males and females. In general, males seemed to be affected more than females in this study for mental health symptoms. For substance use, “Nervous” and “Smoking” showed positive correlation in 2020 and “Hopeless” and “Alcohol” were positively correlated in 2021.CONCLUSIONS:Young adults’ mental health symptoms and substance use has been proven to be affected through the pandemic and this research results even though localized will assist the community and educational institutions to plan better support to assist young adults with better health and wellness initiatives.

Early in the AIDS epidemic there was substantial concern over so-called casual or non-sexual transmission of HIV much of it centered on contact with saliva (sharing an eating utensil or toothbrush). Several epidemiologic studies and national AIDS case surveillance data demonstrated that the transmission of HIV depended on contact with infected body fluids primarily blood and semen. Studies of household transmission of HIV involving family members who shared commonplace activities could not demonstrate passage of the virus. As the epidemic unfolded concerns about casual contact abated and widespread major risk factors such as needle-sharing anal sexual contact and transfusion became the primary epidemiologic focus. Another realignment of emphasis may now be taking place. After about 2 decades the transmission of HIV in industrialized nations has showed some signs of amelioration. Recent surveillance data in the United States and Europe demonstrate a declining acceleration in the reporting of new incident cases of AIDS. Over the past 2 years there has been a substantial decline in AIDS deaths attributed largely to new therapeutic developments and continuing reports of declines in risk-taking. A number of continuing concerns remain however. Younger homosexual men may still be evidencing sexual behaviors that place them at risk and the burden of HIV infection in women is growing. (excerpt)

Adolescents who experience poor mental health may develop chronic pain. Similarly, those with chronic pain may develop mental health symptoms. Little is known concerning how these co-occurring symptoms are associated with adolescent functioning. Our online cross-sectional quantitative study compared the specific nature of challenges to psychosocial functioning, across 4 groups: (1) adolescents with co-occurring chronic pain and mental health symptoms; (2) adolescents who only experience chronic pain symptoms; (3) adolescents who only experience mental health symptoms, and (4) adolescents who do not report either symptom. Participants completed self-report questionnaires assessing pain experiences, mental health symptoms and psychosocial functioning. After controlling for pain intensity, findings revealed significant differences, in physical, social, and family functioning across all groups. Significantly worse physical functioning was reported by adolescents with co-occurring pain and mental health symptoms and those with pain-only symptoms compared with adolescents with mental health-only symptoms and those without symptoms. Social functioning was significantly worse for adolescents who experienced co-occurring chronic pain and mental health symptoms compared with adolescents who experienced pain-only symptoms, and those with no symptoms. Significantly worse family functioning was reported by adolescents with mental health-only symptoms compared with adolescents reporting pain-only symptoms and no symptoms. Results suggest the combined impact of pain and mental health symptoms mainly influences adolescent social functioning. Future research is needed to develop standardised assessment and treatment plans to facilitate a thorough understanding of symptoms presented by adolescents who experience co-occurring pain and mental health symptoms.This study identifies that the combined impact of pain and mental health symptoms influences adolescent social functioning when compared to adolescents who experience pain-only or those without symptoms. Research is needed to develop standardised assessment and treatment plans to fully understand the symptoms presented by adolescents with co-occurring symptoms.

The COVID-19 pandemic exacerbated psychological distress, but limited information is available on the shifts in mental health symptoms and their associated factors across different stages. This study was conducted to more reliably estimate shifts in mental health impacts and to identify factors associated with symptoms at different pandemic stages. We performed a national repeated cross-sectional study at stable (2021), recurrence (2022), and end-of-emergency (2023) stages based on representative general national population with extensive geographic coverage. Anxiety, depression, post-traumatic stress disorder (PTSD) and insomnia symptoms were evaluated by GAD-7, PHQ-9, IES-R and ISI scales, respectively, and their associated factors were identified via multivariable linear regression. Generally, 42,000 individuals were recruited, and 36,218, 36,097 and 36,306 eligible participants were included at each stage. The prevalence of anxiety, depression and insomnia symptoms increased from 13.7-16.4% at stable to 17.3-22.2% at recurrence and decreased to 14.5-18.6% at end of emergency, while PTSD symptom continuously increased from 5.1% to 7.6% and 9.2%, respectively (all significant, P<0.001). Common factors associated with mental health symptoms across all stages included centralized quarantine, frontline work and residence in initially widely infected areas. Centralized quarantine was linked to anxiety, depression, PTSD and insomnia during the stable, recurrence and end-of-emergency stages. Frontline workers exhibited higher risks of anxiety, depression and insomnia throughout these stages. Individuals in initially widely infected areas were more likely to experience depression and PTSD, particularly during the stable and recurrence stages. Stage-specific risk factors were also identified. Lack of outdoor activity was associated with anxiety, depression and insomnia during the stable and recurrence stages. Residents in high-risk areas during the recurrence stage correlated with increased anxiety and insomnia. Suspected infection was tied to anxiety and insomnia in the recurrence and end-of-emergency stages, while the death of family or friends was linked to PTSD during recurrence and to depression, PTSD and insomnia at the end-of-emergency stage. Mental health symptoms increased when pandemic recurred, and could remain after end-of-emergency, requiring prolonged interventions. Several key factors associated with mental symptoms and their variations were identified at different pandemic stages, suggesting different at-risk populations.