Abstract
Recently published Streptomyces genome sequences.
Highlights
Many readers of this journal will need no introduction to the bacterial genus Streptomyces, which includes several hundred species, many of which produce biotechnologically useful secondary metabolites
Many of the recently published Streptomyces genome sequences are assembled from massively parallel sequencing platforms such as 454
The authors of the Mg1 genome project (Hoefler et al, 2013) exploited the PacBio SMRT sequencing technology, which provides sequences reads of several Kb in length, meaning that an entire polyketide synthetases (PK) or non-ribosomal peptide synthases (NRPS) gene could be represented on a single sequence read, avoiding the difficulties of assembling repetitive sequence from short fragments
Summary
Many readers of this journal will need no introduction to the bacterial genus Streptomyces, which includes several hundred species, many of which produce biotechnologically useful secondary metabolites. The last 2 years have seen numerous publications describing Streptomyces genome sequences (Table 1), mostly as short genome announcements restricted to just 500 words and allowing little description and analysis. Our aim in this current manuscript is to survey these recent publications and to dig a little deeper where appropriate. The reasons given for sequencing this latest crop of Streptomyces include production of industrially important enzymes, degradation of lignin, antibiotic production, rapid growth and halo-tolerance and an endophytic lifestyle (Table 1)
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