RECENT USES OF 2,4,6-TRICHLORO-1,3,5- TRIAZINES AND ITS DERIVATIVES

Abstract

Triazines is the chemical species of six-membered heterocyclic ring compounds with three nitrogens replacing carbon-hydrogen units in the benzene ring structure. The names of the three isomers indicate which of the carbon-hydrogen units on the benzene ring position of the molecule have been replaced by nitrogens, called 1,2,3-triazine, 1,2,4-triazine and 1,3,5-triazine respectively. Symmetrical 1,3,5-triazine is the most common. Triazines are prepared from cyanic acid amide by trimerization (1,3,5-triazine). Pyridine is the aromatic nitrogen heterocyclic compound having only one nitrogen and diazines are with two nitrogen atoms, triazines having three nitrogen atoms on the benzene ring system. Triazines are weak bases. Triazines have much weaker resonance energy than benzene, so nuceophilic substitution is preferred than electrophilic substitution. 1,3,5-Triazine or s-triazine moiety, represents an 1-5 interesting class of compounds possessing a wide spectrum of biological activities such as antimalarial, antibacterial, antimycobacterial, antifungal, herbicidal, anticancer, antitumoral and antiviral etc.