Abstract
More than two decades after their clinical introduction, crosslinked polyethylenes (XLPE) have been widely adopted. Though concerns were initially raised regarding oxidation and brittleness, on a large scale, the first generation of XLPE continues to be highly effective 15 years after the surgery, even in a young and active population. Remelted XLPE might display lower wear rates than annealed XLPE. Second generation XLPEs, not only including sequentially irradiated and annealed but also associated with antioxidants, demonstrate encouraging short- to mid-term results. Registry data support clinical trial reports. Even in less favorable settings (lipped liners, dual mobility cups, revision surgery, hip resurfacing) results are promising. However, failures (fractures) have already been described. Therefore, a high level of surveillance remains crucial.
Highlights
Primary total hip arthroplasty (THA) has proven to be highly effective for end-stage hip osteoarthritis
The 15-year wear-related revision rate was lower in the XLPE group (0%) than in the conventional polyethylene (CPE) group (12%; P < 0.001)
Extended reviews have been published about XLPE including vitamin E or other antioxidants [16, 17], but to date, main data are collected from ex vivo experiments or clinical studies with less than 5-year follow-up
Summary
Abstract – More than two decades after their clinical introduction, crosslinked polyethylenes (XLPE) have been widely adopted. Though concerns were initially raised regarding oxidation and brittleness, on a large scale, the first generation of XLPE continues to be highly effective 15 years after the surgery, even in a young and active population. Remelted XLPE might display lower wear rates than annealed XLPE. Second generation XLPEs, including sequentially irradiated and annealed and associated with antioxidants, demonstrate encouraging short- to mid-term results. Even in less favorable settings (lipped liners, dual mobility cups, revision surgery, hip resurfacing) results are promising. A high level of surveillance remains crucial
Sign-in/Register to view highlights & summary Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
