Abstract
Angiotensin receptor blocker(ARB)is acting as an antihypertensive drug at the receptor level.Because of its important roles in improving insulin resistance through dilating the blood vassels via increasing the peripheral tissue perfusion,enhancing the glucose transport and uptake by tissue sensitive to insulin,promoting preadipocyte differentiation,inhibiting the inflammation of the adipose tissue,decreasing the toxicity of free fatty acid,blocking the oxidative stress reaction and modulating the gene expression of angiotensin Ⅱ,ARB has opened up broad prospects for the treatment of type 2 diabetes mellitus with hypertension. Key words: Angiotensin receptor blocker; Insulin resistance; Inflammatory cytokines; Type 2 diabetes mellitus
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