Abstract
The role of commercially available Ammonium chloride in organic synthesis can not be understated. This review summarizes the versatile synthetic applications of Ammonium chloride in different chemical transformations. Reactions include Claisen rearrangement, Ullmann coupling, thia-Michael addition, three- component synthesis of dihydropyrimidinones, imidazo(1,2-a)pyridines, tetrahydrobenzo(a)xanthene-11-ones, benzoxazines, iminooxazolines, imidazo(1,2-a)pyrimidines, spirochromenes, spiroacridines, four-component synthesis of dipeptides, pyrrolo(3,4-b)pyridine-5-ones, crossed-aldol condensation, condensation of carbonyl compounds and indoles, synthesis of quinoxalines, arylbenzothiazoles, bisbenzothiazoles, reduction, and oxidation. Application of this catalyst allows mild and highly selective transformation and synthesis in a facile and environmentally friendly manner. Moreover, Ammonium chloride is an inexpensive and easily available catalyst, which acts under neutral conditons.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
