Abstract

AbstractThe influence of structural variations in compounds of the N‐acylalanine type, on their fungicidal activity towards Peronosporales, was examined. Within a series of methyl N‐(acyl)‐N‐(2,6‐xylyl)alaninates (I), a quantitative structure‐activity relationship was given for the curative action against Plasmopara viticola, through a Hansch‐type equation. A deviation from this equation is discussed with reference to benalaxyl (I; acyl=phenylacetyl). Syntheses and qualitative indications of activity are reported for structural changes in the xylyl and in the alanine moieties. Progress in the latter approach is briefly outlined.

Full Text
Published version (Free)

Talk to us

Join us for a 30 min session where you can share your feedback and ask us any queries you have

Schedule a call