Abstract
The majority of advances in cancer therapy have been achieved based on developments in public awareness, as well as novel diagnostic and therapeutic modalities. Treatment breakthroughs such as nanotheranostics and innovative nano-based solutions have profoundly contributed to improved cancer diagnosis, control, and treatment, and tackled the drawbacks of conventional therapies. Nanotheranostics is being developed to realize the potential of personalized medicine by assisting in the choice of therapies, the objective monitoring of response, and the planning of follow-up therapy. Polymersomes have numerous advantages for serving as theranostics and are designed and fabricated to form intelligent and sustained-releasing drug formulations. Biocompatible and/or biodegradable polymersomes vary in size and charge and show trifling cytotoxicity to normal tissues in vivo. Taking note of these properties, polymersomes are currently becoming popular theranostic nanoparticles since they are being exploited as simultaneous drug-delivery and imaging platforms. Here, we focus on how an effective nanotheranostic platform may be created using a unique type of polymersome cluster filled with active chemicals. This review looks through recent progress in the application of functionalized polymersomes and chimeric polymeric nanotheranostic platforms to improve tailored cancer therapy.
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