Abstract
According to the WHO approximately 350 million individuals worldwide are affected by depression, making it the global leading cause of disability. Depression also closely associates with suicide. The last three decades have seen a wealth of genetic studies aiming to identify genes associated with depression and suicidal behavior, whereas more recent advances in our understanding of how the genome is functionally regulated, coupled with developments in high-throughput sequencing methods, have led to an increased capacity and interest in the study of functional genomics. These studies provide us with a unique opportunity to understand how the brain is regulated and to more directly investigate genomic processes that may be at fault in the depressed and suicidal brain. In this review, we discuss recent advances in studies investigating transcriptomic and epigenomic studies of depression and suicide.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
