Recent progress in cycloaddition reactions of cyclopropenone

Abstract

Cyclopropenone has emerged as a highly versatile precursor in organic synthesis due to its diverse reactivity. The cyclopropenone derivatives could undergo various transformations such as cycloaddition reactions, ring-opening reactions, and isomerization reactions in the presence of different chemical reagents. Over the years, significant progress has been made in the manipulation of cyclopropenones for the construction of various carbocycles, heterocycles, and other useful organic compounds. Despite several reviews that have concerned the chemistry and reactions of cyclopropenones, the utility of such motifs in the construction of carbocycles and heterocycles has rarely been reported. Herein, we report recent advancements in the cycloaddition reactions of cyclopropenones as versatile synthetic precursors towards the synthesis of compounds with synthetic and biological significance.