Recent progress in biomedical materials modified by polydopamine

Abstract

Dopamine (DA), which not only contains catechols, but also includes amino substances. Because DOPA derivative is dopamine, it's essentially the same as DOPA. According to the study of related experts, such as Lee, DA will self-react in the alkaline aerobic humid environment, and PDA nanofilms containing catechol units will be generated on the surface of the substance. The preliminary work showed that polydopamine (PDA) showed excellent advantages in adsorption and bio-compatibility in vivo. In addition, because of its excellent chemical properties, PDA can be used as a "platform" for "secondary modification", grafting a variety of functional small molecules onto the matrix, so as to improve the matrix's osteogenic, antibacterial properties. This paper briefly introduces the research progress of PDA in medical materials and other aspects in order to lay a foundation for PDA to be used more in medical materials research and development.