Abstract

Cardiorenal syndrome is a clinical condition in which there is a correlation between heart and kidney diseases. In recent times, many biomarkers have been studied in patients with cardiovascular diseases for developing proper knowledge of renal function and identifying patients who are more susceptible to chronic or acute deterioration of renal function. Because diagnostic and prognostic usefulness of a single time point biomarker is limited, biomarkers should be combined and monitored at multiple times for optimal clinical impact. This review mainly lays emphasis on the potential clinical uses of the biomarkers in cardiorenal syndrome, recent advancements of biomarkers in developing therapeutic agents for Alzheimer’s disease, and classification of different types of biomarkers as well as highlights classic heart failure biomarkers with critical values adjusted to glomerular filtration rate and summarizes research progress of new heart failure biomarkers and future research directions.

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