Abstract
Asymmetric three-component Kabachnik-Field reaction for the stereoselective synthesis of optically active α-amino phosphonates has been received considerable attention due to their great intrinsic advantages as well as their applica- tions in drug discovery. This review covers recent progress on asymmetric three-component Kabachnik-Field reaction includ- ing the chiral catalysts and optical active substrate induction approaches to chiral α-aminoalkylphosphonic acid derivatives. The influence of the chiral catalysts and reaction substrate configuration on the reaction stereoselectivity is the major focus. It elicits issues and perspectives of asymmetric three-component Kabachnik-Field reaction in the end. Keywords Kabachnik-Fields reaction; asymmetric synthesis; chiral α-aminoalkylphosphonic acid 多组分反应(multicomponent reactions, MCRs)是指
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
