Abstract

Recent investigations of ergot alkaloids incorporated into plant and/or animal systems.

Highlights

  • Ergot alkaloids have been associated with endophyte-infected grasses with examples including tall fescue and fescue toxicosis in the United States (Yates et al, 1985) as well as perennial ryegrass in New Zealand (Rowan and Shaw, 1987) and Ireland (Canty et al, 2014)

  • While ergot alkaloid incidences are rare in humans resulting from increased regulation of grain processing (Flieger et al, 1997; EFSA, 2012), reports are still present from occasional pharmacological overdose or accidental exposure (e.g., Stange et al, 1998)

  • While difficult to place an exact dollar amount on the global cost from ergot alkaloids, several estimates regarding the cost of ergot alkaloids have been projected in the southern United States

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Summary

Introduction

Ergot alkaloids have been associated with endophyte-infected grasses (e.g., the Epichloë, Bacon et al, 1977 and Balansia, Porter et al, 1979 spp.) with examples including tall fescue and fescue toxicosis in the United States (Yates et al, 1985) as well as perennial ryegrass in New Zealand (Rowan and Shaw, 1987) and Ireland (Canty et al, 2014). The result has been increased occurrences of ergot alkaloid issues arising in areas not typically associated with pasture-based agriculture. In addition to these incidents, grasses can become infested with Claviceps purpurea where the alkaloids, typically ergotamine and ergocristine, are responsible for the resultant ergotism associated with C. purpurea.

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