Abstract
The need for blood transfusion is one the rise because of rapid population growth, development of new infections, accidents and natural disasters. One of the future evolutionary innovations could be artificial blood substitutes which is the most important need in transfusion medicine. Encapsulation of hemoglobin within a liposome is one of the recent strategies in the production of artificial oxygen carriers. In this review we summarize the role of liposome encapsulated haemoglobin (LEH) as artificial oxygen carrier. In addition, the steps taken toward the development of LEH as artificial blood technology and some of their applications and limitations were highlighted.
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