Recent emerging gut Microbiome Management Modalities in Acute Diarrhea in Children: (a comparative study review of different probiotic strains). An Update. !

Amr I.M Hawal

doi:10.31579/2690-8808/023

Abstract

Aims & Objectives: Acute Diarrhea (AD) is a highly prevalent condition that causes significant morbidity and mortality worldwide. Conventional therapies include oral Rehydration Solutions (ORS), Antibiotics and Zinc Products. Emerging data suggest that Probiotics use in the treatment & control of AD cases in children may help supplement current therapies for further control. Methods Herein, we review the evidence of several Probiotics modalities for AD treatment. We describe the Clinical Impact & prevalence of Acute Diarrhea in children and its complications, provide an overview of current treatments, and finally, discuss recent emergent Gut approaches to AD management. Specifically, we will describe - in a Comparative study - on the utility of different kinds of Probiotics known & used and common natural products in the treatment of Acute cases of AD and focus on recent, high-quality studies. Adverse effects and potential interactions of each therapy will be highlighted where applicable.

Highlights

Acute Diarrheal Diseases considered as the most common leading causes of children mortality all over the globe
** Bifidobacterium bifidum reported that one strain (CIDCA5310) inhibited enterocyte invasion by Salmonella arizonae, whereas the other (CIDCA 537) had no effect
Do probiotics work in Acute Infectious Diarrhea?

Summary

Introduction

Acute Diarrheal Diseases considered as the most common leading causes of children mortality all over the globe. Only 39 per cent of children with Diarrhea in developing countries receive the recommended treatment, and limited trend data suggest that there has been little progress since 2000, more than 386000 children dies in India only due to A. An international commitment to tackle childhood Diarrhea in the 1970s and 1980s resulted in a major reduction in child deaths. This came about largely through the scaling up of oral rehydration therapy, coupled with programs to educate caregivers on its appropriate use. These efforts lost momentum as the world turned its attention to other global emergencies

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