Abstract
Recent developments in the preparation of homoallyl-amines or (homo)propargylamines via three-component Grignard-Barbier-type reactions are reviewed. The multicomponent coupling strategy that allows quick access to these compounds is discussed. 1 Introduction 2 Homoallylamines 2.1 Preparation with Allylmetal Species Formed in situ 2.2 Preparation with Presynthesized Allylmetal Species 3 Homopropargylamine Synthesis from Prepared Imines Forming in situ Propargylmetal Species 4 Propargylamines 4.1 Preparation via Alkynylation of Imines 4.2 Preparation via Aldehyde-Alkyne-Amine (A 3 ) Coupling 5 Perspectives
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