Abstract

Purpose of reviewThe aim of this review was to summarize key developments in classification and diagnosis of the idiopathic inflammatory myopathies (IIMs).Recent findingsThe recently published European League Against Rheumatism/American College of Rheumatology (EULAR/ACR) classification criteria for the IIMs provide a comprehensive, accurate and data-driven approach to identification of IIM cases appropriate for inclusion in research studies. Further, recent studies have advanced understanding of clinical manifestations of the IIMs and delineated the role of imaging, particularly magnetic resonance.SummaryThe recent publication of the EULAR/ACR classification criteria will potentially greatly improve IIM research through more accurate case identification and standardization across studies.Future inclusion of newly recognized clinical associations with the MSAs may further improve the criteria's accuracy and utility. Clear and comprehensive understanding of associations between clinical manifestations, prognosis and multisystem involvement can aid diagnostic assessment; recent advances include delineation of such associations and expansion of the role of imaging.

Highlights

  • The idiopathic inflammatory myopathies (IIMs) are a group of autoimmune diseases characterised by chronic muscle inflammation, internal organ inflammation and significant morbidity and mortality [1]

  • A Medline search for research articles published between January 2017 and May 2018 was carried out using the MeSH term ‘myositis’

  • Articles primarily focussing on myositis-specific autoantibodies were excluded, as they will be reviewed in detail in a separate article

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Summary

INTRODUCTION

The idiopathic inflammatory myopathies (IIMs) are a group of autoimmune diseases characterised by chronic muscle inflammation (myositis), internal organ inflammation and significant morbidity and mortality [1]. The Bohan and Peter criteria demonstrate a high degree of accuracy and usefulness in research and clinical settings This usefulness is limited by a number of factors, including lack of specification of how to exclude other forms of myopathy and aNIHR Manchester Musculoskeletal Biomedical Research Centre, Manchester University Hospitals NHS Foundation Trust, Manchester Academic Health Science Centre, bCentre for Musculoskeletal Research, Manchester Academic Health Science Centre, The University of Manchester, Manchester and cRheumatology Department, Salford Royal NHS Foundation Trust, Manchester Academic Health Science Centre, Salford, UK.

KEY POINTS
Objective symmetric
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