Recent Bio-medical applications of iron oxide magnetic nanoparticles

Abstract

In recent times, pronounced consideration has been dedicated to the amalgamation of several magnetic nanoparticles because of their widespread smart and encouraging biological solicitations. The magnetic IONPs, magnetite (Fe3O4 DQG PDJKHPLWH Ȗ-Fe2O3) have shown some remarkable applications in nanomedicines, diagnosis tools, and pharmaceuticals. Iron oxide magnetic nanoparticles (IOMNPs) have been explored for an extensive collection of biomedical and healthcare solicitations built on their surface properties, biocompatibility, and exceptionally, great magnetic susceptibility. In this logic, the magnetic properties of IOMNPs permit their usage in numerous biomedical applications, such as targeted drug delivery, hyperthermia, magnetic tissue engineering, MRI contrast agents, in vitro magnetic bio separation, bio-analysis, magnetic transducers, and theranostic platforms. The functionalized hybrid IOMNPs have also been utilized against fungal infections and numerous pathogenic strains of microorganisms. Iron oxides play a significant role in the field of bio-catalysis, nanotechnology, and bio-medicines; therefore they are the main focus of this review. Keeping in mind the state-of-the-art, this review is intended to report the latest information about IOMNPs from methods of synthesis to modern bio-medical applications. Moreover, in-vivo and in-vitro uses of IOMNPs have conversed in detail. The challenges and restrictions in the biological usage of IOMNPs are also highlighted. This review based on IOMNPs will deliver a convincing vision for the investigators in nano-biotechnology and pharmacy