Abstract
Abstract Qualitative Fourier transform infrared (FTIR) spectroscopy has long been established and implemented in a wide variety of fields including pharmaceutical, biomedical, and clinical fields. While the quantitative applications are yet to reach their full potential, this technique is flourishing. It is tempting to shed light on modern engaging and the applicability of analytical quantitative FTIR spectroscopy in the aforementioned fields. More importantly, the credibility, validity, and generality of the application will be thoroughly demonstrated by reviewing the latest published work in the scientific literature. Utilizing FTIR spectroscopy in a quantitative approach in pharmaceutical, biomedical, and interdisciplinary fields has many undeniable advantages over traditional procedures. An insightful account will be undertaken in this regard. The technique will be introduced as an appealing alternative to common methods such as high performance liquid chromatography. It is anticipated that the review will offer researchers an update of the current status and prospect on the subject among the pharmacy and biomedical sciences both in academic and industrial fields.
Highlights
Qualitative Fourier transform infrared (FTIR) spectroscopy has long been established and implemented in a wide variety of fields including pharmaceutical, biomedical, and clinical fields
The signal-to noise ratio (SNR) of a peak in an IR spectrum is a vital measure of spectral qualities
The basic principle behind the quantitative nature of the technique is attributed to the fact that the quantized absorption of energy by analytes at certain wavelengths is directly proportional to the concentration of functional groups present [9]. Due to their low cost, high accuracy, and precision, many researchers investigated the development of FTIR analytical techniques for the quantitative analysis of different pharmacological groups in pure form and certain pharmaceutical dosage forms (Table 2)
Summary
Abstract: Qualitative Fourier transform infrared (FTIR) spectroscopy has long been established and implemented in a wide variety of fields including pharmaceutical, biomedical, and clinical fields. It is tempting to shed light on modern engaging and the applicability of analytical quantitative FTIR spectroscopy in the aforementioned fields. Utilizing FTIR spectroscopy in a quantitative approach in pharmaceutical, biomedical, and interdisciplinary fields has many undeniable advantages over traditional procedures. The infrared (IR) spectroscopy has been mainly used in analytical chemistry applications for qualitative outcomes, that is, to obtain general and wide analytical qualities of a broad range of samples. IR spectroscopy is a result of molecular absorption of energy from a passing electromagnetic radiation in the IR frequency regions. Recent FTIR technique developments rendered the tool as applicable to both quantitative and qualitative purposes of analyses [2,3]
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