Recent Advances on the Synthesis of Orally Active Antiviral Drug Molnupiravir

Abstract

Abstract: Molnupiravir is one of the simple orally active antiviral drugs, sold under the brand name Lagevrio. Initially, this drug was used to treat the influenza virus but later on, used against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). This is the first orally active and direct-acting antiviral drug and is highly effective against SARS-CoV- 2. In this review, we discuss different synthetic strategies for the synthesis of molnupiravir, which will help for the further development of novel routes.