Abstract

Abstract Recent studies have shown that butanol is a potential gasoline replacement that can also be blended in significant quantities with conventional diesel fuel. However, biotechnological production of butanol has some challenges such as low butanol titer, high cost feedstocks and product inhibition. The present work reviewed the technical and economic feasibility of the main technologies available to produce biobutanol. The latest studies integrating continuous fermentation processes with efficient product recovery and the use of mathematical models as tools for process scale-up, optimization and control are presented.

Highlights

  • During the last decade the interest in the production of chemicals and fuels from renewable resources has increased

  • According to Ezeji et al [40], the production of ABE increased from 18.6 g/L to 81.3 g/L, whereas sugar consumption increased about 487% using gas stripping in the fermentation of liquefied corn starch with C. beijerinckii BA101

  • Concluding remarks In this review, biobutanol production was discussed in terms of microorganisms, substrates, types of bioreactors used in the process, separation techniques with special attention to in situ separation leading to decrease butanol inhibition and, the development of mathematical models to represent the in situ separation techniques

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Summary

Introduction

During the last decade the interest in the production of chemicals and fuels from renewable resources has increased. The problems in the use of cellulosic or lignocellulosic materials for butanol production are the processes for production of these hydrolysates, resulting in the generation of chemical byproducts that inhibit cell growth and fermentation. Concluding remarks In this review, biobutanol production was discussed in terms of microorganisms, substrates, types of bioreactors used in the process, separation techniques with special attention to in situ separation leading to decrease butanol inhibition and, the development of mathematical models to represent the in situ separation techniques. The engineering of microorganisms for butanol production has been reported over recent years These changes in the bacterium decrease acetone production as well as increasing the resistance of microorganisms to high concentrations of butanol with consequent improvement in the use of sugar as a substrate for biobutanol production.

13. Taylor G
16. Vane LM
22. Qureshi N
Findings
27. Dürre P
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