Abstract
Over the last few years, treatment of severe symptomatic aortic stenosis in high-risk patients has drastically changed to adopt a less-invasive approach. Transcatheter aortic valve implantation (TAVI) has been developed as a very reproducible and safe procedure, as shown in many trials. When compared to surgery, TAVI has produced superior, or at least comparable, results, and thus a trend to broaden treatment indications to lower-risk patients has erupted as a natural consequence, even though there is a lack of long-term evidence. In this review, we summarize and underline aspects that still remain unanswered that are compulsory if we want to enhance our understanding of this disease.
Highlights
Introduction and historical backgroundAortic stenosis (AS) is the most common heart valve disease worldwide, ranging from 2–4% in patients older than 75 years of age[1,2]
We summarize and underline aspects that still remain unanswered that are compulsory if we want to enhance our understanding of this disease
Many patients have been treated with Transcatheter aortic valve implantation (TAVI) and similar results were achieved
Summary
Introduction and historical backgroundAortic stenosis (AS) is the most common heart valve disease worldwide, ranging from 2–4% in patients older than 75 years of age[1,2]. Results Many trials have already shown efficacy and even better outcomes than surgery in selected high surgical risk patients[7,8,10,11].
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