Abstract
Magnesium (Mg) and its alloys have gained significant attention in orthopedic applications due to their biocompatibility, mechanical properties, and biodegradability. However, the rapid degradation of Mg implants in the physiological environment poses a significant challenge to their clinical application. Post-treatment of Mg scaffolds has been extensively studied to improve their corrosion resistance and biocompatibility, and recent advances have shown promising results. This review article summarizes and discusses the recent advances in the post-treatment of Mg scaffolds, including surface modification, surface functionalization, and incorporation of bioactive agents. The advantages and disadvantages of each technique are presented. Additionally, this review highlights the challenges associated with Mg-based implant development and future directions for research in this field. The recent advances in the post-treatment of Mg scaffolds hold great potential for developing biodegradable orthopedic implants with improved clinical outcomes.
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