Abstract

2-Cyanoacrylates are a unique class of compounds with high photosystem II electron transport inhibitory activity. Through the in-depth study of molecular design, synthesis, biological activity, structure-activity relationship, and action mechanism, a large number of 2-cyanoacrylate derivatives with excellent herbicidal activity were found. In addition, 2-cyanoacrylate derivatives with different substituents have also been found to have good fungicidal or anti-plant virus activities. To further guide the design and development of new pesticide candidates, the representative research work of 2-cyanoacrylate derivatives with herbicidal, fungicidal, and anti-plant virus activities was reviewed.

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