Recent advances in photocatalyzed reactions using well-defined copper(I) complexes.

Mingbing Zhong,Xavier Pannecoucke,Philippe Jubault,Thomas Poisson

doi:10.3762/bjoc.16.42

Abstract

This review summarizes the recent advances in photocatalysis using copper complexes. Their applications in various reactions, such as ATRA, reduction, oxidation, proton-coupled electron transfer, and energy transfer reactions are discussed.

Highlights

For a decade, the realm of catalysis has known a significant renewal with the rise of photocatalysis [1]
Photocatalysis allows carrying out photochemical reactions in the visible region
As most organic molecules absorb light in the UV region (UV-A, UV-B, or UV-C), selectivity was a key point to address in photochemistry and photocatalysis using visible light tackled this issue

Summary

Introduction

The realm of catalysis has known a significant renewal with the rise of photocatalysis [1]. To explain the reaction outcome, the authors suggested the following mechanism: The excited copper catalyst reduces the CF3SO2Cl reagent, resulting in the formation of a sulfonyl radical, which, after elimination of SO2, generates the trifluoromethyl radical This radical reacts with the olefin to form a carbon-centered radical. In 2018, during the development of a combinatorial approach to select the best copper-based photocatalyst, Collins and co-workers reported the synthesis of a bicyclic lactone by a PCET reaction manifold (Scheme 32) [39] Using their methodology, the authors discovered the [Cu(I)(quinitri)(xantphos)]BF4 catalyst as the best one, which afford the cis-lactone in 79% isolated yield. The reaction was promoted by a visible-light irradiation (450 nm) using the complex [Cu(I)(dmp)(BINAP)]BF4, and the desired pyrrole was obtained in quantitative yield

Conclusion

Findings

For instance