Abstract

Over the past two decades, the nucleophilic phosphine catalysis has effected many powerful annulation reactions and emerged as an intriguing platform for the generation of highly functionalized carbo‐ and heterocycles. In addition to the well‐established (3 + 2) annulation, the phosphine‐promoted (4 + 1) annulation has received increasing attention and developed rapidly in recent years, which complements the (3 + 2) annulation and also provides an alternative approach to structurally diverse five‐membered carbo‐ and heterocycles. This minireview summarizes the recent advances in phosphine‐promoted (4 + 1) annulation reactions according to the type of substrates used in the annulations.

Talk to us

Join us for a 30 min session where you can share your feedback and ask us any queries you have

Schedule a call

Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.