Recent advances in management of acute promyelocytic leukemia

Abstract

Acute promyelocytic leukemia (APL) is a special subtype of acute myeloid leukemia. Its main clinical features are severe coagulopathy, bleeding tendency and high early mortality. With the continual advances in APL research, APL has become a kind of curable leukemia with the highest cure rate at present. In order to further guide the therapy of APL and improve the quality of life of patients with APL, this article reviews current advances of treatment of APL. Key words: Leukemia, promyelocytic, acute; Arsenic trioxide; All-trans retinoic acid