Abstract
Over the decades with the outcome of industrial compliance, manufacturing process, formulation and development, Hot Melt Extrusion (HME) has also expanded the acceptance. As a result of industrial adaptability, it has developed itself in a wide range as a part of pharmaceutical research and development. New drug entities face failures or delays during formulation development, including poor biopharmaceutical properties, toxicities and lack of efficacy. To overcome such obstacles, HME technique is most preferred one. In comparison to conventional techniques, its use has been increasing because of its convenient process, solvent free nature, cost effective and on-line manufacturing. For achieving different applications several dosage forms can be produced by altering the design of equipment and adapting a modified processing condition.
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