Abstract
Hepatocellular carcinoma (HCC) is a leading cause of cancer-related morbidity and mortality worldwide, largely as a result of 3 main factors: (1) competing risk of cirrhosis, which accompanies 80% to 90% of HCC diagnoses; (2) ineffective early detection programs; and (3) a historical lack of effective therapies, specifically for patients with intermediate- or advanced-stage disease. 1 Yang J.D. Hainaut P. Gores G.J. et al. A global view of hepatocellular carcinoma: trends, risk, prevention and management. Nat Rev Gastroenterol Hepatol. 2019; 16: 589-604 Crossref PubMed Scopus (718) Google Scholar Although the burden of HCC is projected to increase, several recent advances in HCC therapeutics allow for optimism as new treatment algorithms are developed to improve patient quantity and quality of life.
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