Abstract
Interest in the development of extraction of phytochemicals compounds from Clinacanthus nutans has increased in recent years due to its potential applications in food, chemical, and pharmaceutical industries. The quality and yield of the phytochemicals are greatly influenced by the extraction method employed as well as other factors. This paper provides an up-to-date overview of traditional (maceration, infusion, and soxhlet), with modern methods (pressurized hot water extraction, supercritical fluid extraction, ultrasound-assisted extraction, and microwave-assisted extraction) to extract phytochemicals compounds from C. nutans. Problems associated with conventional extraction methods have led to a demand for alternatives and indeed several new extraction methods have been developed and refined in the last two decades that can efficiently extract a great variety of valuable bioactive compounds.
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