Abstract

In this invited review, we provide an overview of the recent advances in biomedical photonic sensors within the last five years. This review is focused on works using optical-fibre technology, employing diverse optical fibres, sensing techniques, and configurations applied in several medical fields. We identified technical innovations and advancements with increased implementations of optical-fibre sensors, multiparameter sensors, and control systems in real applications. Examples of outstanding optical-fibre sensor performances for physical and biochemical parameters are covered, including diverse sensing strategies and fibre-optical probes for integration into medical instruments such as catheters, needles, or endoscopes.

Highlights

  • For an extended list of reviews of optical-fibre sensors focused on biomedical applications, the reader is referred to Table S1 in the supporting information

  • When a BPS is equipped with some kind of intelligence and provides actuation signals, it is some kind of intelligence and provides actuation signals, it is transformed into a Biomedical Smart transformed into a Biomedical Smart Photonic Sensor (BSPS)

  • 5.5.Summary and Conclusions review latest results biomedical photonic sensors based on optical review of of thethe latest results on on biomedical photonic sensors based on optical fibresfibres has has been presented

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Summary

Introduction

The interaction between light and biological cells, tissues, organs, and body signals has enabled significant contributions of photonics to the medical field [1]. In this rePresently, the application of optical-fibre sensors technology is increasing (Figure 1a) gard, fibre Bragg grating or interferometric sensors (e.g., Fabry–Pérot cavities) are widely and progressively reaching maturity in specific biomedical applications [12] In this regard, used monitor physical parameters. 1b, which to shows network map of keywords evanescent field) sensors are primarily investigated detecta biological/chemical paramefound in journal articles related to optical-fibre sensors for biomedical applications ters. This map highlights the sensing techniques, parameters, etc., employed in each cluster groups a series of keywords sharing high linking strength between them This the biomedical field over the years. The evolution of published articles over the years and network maps of keywords related to optical-fibre sensors in general (not restricted to the biomedical field) can be found in the supporting information (Figures S1 and S2), including details on how these graphs were generated. For an extended list of reviews of optical-fibre sensors focused on biomedical applications (or with biomedical interest), the reader is referred to Table S1 in the supporting information

Biomedical Photonic Sensors
Physical Parameters
Temperature
Vital-Sign Monitoring
Biochemical Parameters and Biosensors
Optrode
Oxygen
Cancer-Related
Multiparameter Sensing and Lab-on-Fibre
Fibre-Optical Probes for Spectroscopy
Reflectance Probes
Fluorescence Probes
Modified Fibre-Optical Probes
Fibre Bragg Gratings
Fabry–Pérot
Findings
Summary and Conclusions
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