Abstract
Asymmetric reactions are carried out by organocatalysis in many ways, making them very competitive and practical. One remarkable molecule, the amino acid proline, has become a crucial component in organocatalysis because of its ability to promote chemical transformations with high enantioselectivity. The following review discusses the contributions and recent advances in the field of asymmetric reactions catalyzed by l -proline and its derivatives. 1 Introduction 2 Asymmetric Aldol Reactions Catalyzed by Proline and Its Derivatives 2.1 Reactions of Ketones as Aldol Donors with Aldehydes as Aldol Acceptors 2.2 Reactions of Aldehydes as Aldol Donors with Aldehydes as Aldol Acceptors 2.3 Reactions of Aldehydes as Aldol Donors with Active Ketones as Aldol Acceptors 2.4 Reactions of Ketones as Aldol Donors with Active Ketones as Aldol Acceptors 3 Asymmetric Mannich Reactions Catalyzed by Proline and Its Derivatives 4 Asymmetric Michael Reactions Catalyzed by Proline and Its Derivatives 5 Asymmetric α-Amination Reactions Catalyzed by Proline and Its Derivatives 6 Conclusion
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
