Abstract

The nitroso Diels—Alder (NDA) reaction has occupied an important place in organic synthesis, and numbers of important compounds and bioactive skeletons have been synthesized by this method during the past decade. Good regiocontrol and enantioselectivity of the NDA reaction allow it to have wider application. This microreview discusses the latest advances in the area of asymmetric NDA reactions and their synthetic applications since Yamamoto’s detailed summary made in 2006.

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