Abstract
Droplet-based microfluidics is a colloidal and interfacial system that has rapidly progressed in the past decade because of the advantages of low fabrication costs, small sample volumes, reduced analysis durations, high-throughput analysis with exceptional sensitivity, enhanced operational flexibility, and facile automation. This technology has emerged as a new tool for many recently used applications in molecular detection, imaging, drug delivery, diagnostics, cell biology and other fields. Herein, we review recent applications of droplet microfluidics proposed since 2013.
Highlights
Microfluidics appeared in the early 1980s as a promising interdisciplinary technology and has since received considerable attention
We review the applications of droplet microfluidics, which are categorized as follows: molecular detection, imaging, drug delivery, diagnostics, cell biology, and other applications
In addition to the described applications in molecular detection, imaging, drug delivery, diagnostics, and cell biology, droplet microfluidics can be applied in many other fields
Summary
Microfluidics appeared in the early 1980s as a promising interdisciplinary technology and has since received considerable attention. The fundamental of these droplet-based microfluidic reagents samples,integration reduced analysis times, improved increased platforms with and high-level include fine controlsensitivity, of small lowered sample detection volumes,limits, reduced amounts of high-throughput screening, enhanced operational flexibility [9]. Seiffert et al proposed faster droplet production light illumination and a standard high-speed camera for studying the fluid dynamics of rapid processes by delayed surfactant-addition to push droplet-based microfluidics to an industrially relevant scale [18]. Isgor et al developed a a reliability-oriented placement algorithm for reconfigurable digital microfluidic biochips by using a 3D deferred decision making technique to optimize bioassay completion times [27]. We review the applications of droplet microfluidics, which are categorized as follows: molecular detection, imaging, drug delivery, diagnostics, cell biology, and other applications
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