Recent Advancements of Microspheres for The Management of Diabetes

Abstract

Diabetes is a chronic metabolic disorder that is accompanied by the inability of the body to regulate blood sugar level. The prevalent lifestyle and diet habits have increased the number of diabetic individuals to a large number. The novel treatment options have been explored to manage diabetes and overcome the risks associated with the existing therapy. Some of the recent researchers have prepared advanced microspheres either for the delivery of anti-diabetic drugs and insulin or for diagnostic purposes. These microspheres allow the development of controlled or sustained delivery products with rapid onset of action and improved bioavailability. The fabrication of surface-modified microspheres has shown significant promise in achieving the therapeutic goal of diabetes. Glucose-sensitive microspheres can control the release of insulin for a longer duration and improve the hypoglycemic effect of the product. Apart from these, specially designed microspheres were utilized for early detection of diabetes and study disease progression. This review is aimed at providing a perspective over some of the important recent researches with regards to treatment and diagnosis of diabetes. Microspheres have offered a lot of potential for integrating innovative strategies in the treatment and diagnosis of diabetes. The scalability and real-life interventions of these approaches might still be a challenge that need to be addressed.