Abstract
The rapid advancement of nanotechnology has revolutionized the field of biomaterials for applications in biomedical and regenerative medicine. With distinctive physicochemical properties and individualized functionalities, nanostructured biomaterials hold enormous potential for addressing critical issues in tissue engineering, drug delivery, and implantable medical devices. This review examines the most recent advancements and applications of nanostructured biomaterials. This review emphasizes the significance of size, shape, surface charge, and biocompatibility for assessing therapeutic efficacy and cellular interactions by considering the synthesis and characterization of various nanostructured biomaterials, including nanoparticles, nanofibers, and nanocomposites. This review also explores the function of nanostructured biomaterials in overcoming immunological obstacles, promoting the integration of implants and tissue-engineered constructs within the host, and in diverse applications such as vehicles for controlled drug and gene delivery, wound dressing, and cancer therapy. Furthermore, integrating nanotechnology and biomaterials has opened up new frontiers in regenerative medicine, which has the potential to have a revolutionary impact on the future of healthcare and personalized medical interventions.
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