Recent advancements in metal-organic frameworks composites based electrochemical (bio)sensors.

Abstract

Metal-organic frameworks (MOFs) are a novel class of crystalline materials which find widespread applications in the field of microporous conductors, catalysis, separation, biomedical engineering, and electrochemical sensing. With a specific emphasis on the MOF composites for electrochemical sensor applications, this review summarizes the recent construction strategies on the development of conductive MOF composites (post-synthetic modification of MOFs, in situ synthesis of functional materials@MOFs composites, and incorporating electroactive ligands). The developed composites are revealed to have excellent electrochemical sensing activity betterthan their pristine forms. Notably, the applicable functionalized MOFs to electrochemical sensing/biosensing of various target species are discussed. Finally, we highlight the perspectives and challenges in the field of electrochemical sensors and biosensors for potential directions of future development.