Abstract
The emergence of 2D nanomaterials, especially MXenes, have opened new frontiers in the biomedical field. MXenes exhibit unique physicochemical properties, including high surface area, excellent conductivity and biocompatibility, making them ideal candidates for biomedical applications. This review explores the multifaceted roles of MXenes in breast cancer, emphasizing their potential in targeted drug delivery, enhanced imaging and combined therapeutic strategies. We have highlighted MXene-based drug delivery systems that provide precise targeting of cancer cells, minimize adverse effects, and improve therapeutic efficacy. Additionally, remarkable imaging capabilities of MXene enable high-sensitivity and high-resolution visualization of tumors through modalities such as magnetic resonance imaging (MRI), computed tomography (CT), and photoacoustic imaging (PAI). Despite the promising applications, the scalability of MXene synthesis and their biocompatibility remain critical areas for ongoing research. The functionalization of MXenes for specific targeting and therapy presents opportunities for highly effective treatments, particularly in ligand-based and molecularly targeted approaches. Future advancements in synthesis methods, comprehensive in vivo studies and robust safety assessments are essential for translating these materials from the laboratory to clinical settings.
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