Abstract
Surfactant are surface-active agent, which reduce or lower the interface tension between two phase systems. Such concept were utilized in the drug delivery, surfactant vesicles (SV) niosomes. Niosomes are second generation of liposome which slightly different in composition of liposomes. Surfactant play significant role for noisome formation and utilization of different surfactant can possess different properties depending upon the surfactant such as bola surfactant, gemini surfactant. Bola surfactant niosomes have been used as topical for the treatment to skin cancer. Gemini based surfactant niosomes they are main comprised of amino acid-based surfactants and they have shown good penetration enhancer of drug into the skin. Gemini based niosomes able to delivery of anti-diabetics, chemotherapeutics, analgesic and antibiotics to treat different diseases. Surfactant vesicles are more prominent in delivering the drugs in controlled manner to skin through topical and transdermal route.
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