Abstract
The endocannabinoid system has wide-ranged effect on human sleep, pain, mood, metabolism, and neurodevelopment. As one of the members of this system, cannabinoid receptor 1 plays an important protective effect on some neurodegenerative diseases, such as multiple sclerosis disease, Huntington's disease, and Alzheimer's disease. This article aims to outline the protective mechanism of endocannabinoid system and cannabinoid receptor 1 in neurodegenerative diseases. Key words: Cannabinoid receptor 1; Central nervous system disease; Multiple sclerosis; Huntington's disease; Alzheimer's disease
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