Abstract
Glutamatergic system plays an important role in compulsive and/or addictive behaviors [5], which are associated with environmental cues [1]. Topiramate notably blocks the AMPA/kainate subtype of glutamate receptors [4]. Diverse studies and case reports have recently raised the interest of topiramate in the treatment of addictive disorders [6], obesity, and weight gain associated with antipsychotic drugs [2]. Despite this promising treatment for obesity [3], duration of treatment and its modality cessation remain understudied till to date.
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